Faculty members

Isabelle Sermet-Gaudelus

Isabelle Sermet-Gaudelus is a professor in Paediatric at the Necker-Enfants Malades Hospital, Paris France.
She graduated from the University Paul Sabatier, Toulouse in 1989 and undertook clinical trainings in Paediatrics in Paris, Assistanec Publique Hopitaux de Paris. She became involved in Cystic Fibrosis during her fellowship under the supervision of Pr G Lenoir.
She is now the head of the paediatric Cystic Fibrosis center, at the Necker-Enfants Malades Hospital.
She has been engaged for several years in a programme of phenotype-genotype studies, using epithelial electrophysiological measurements (nasal potential difference, intestinal current measurement and more recently evaporimetry).
She works closely on a number of commercially-sponsored clinical trials in CF, largely involving novel small-molecules directed at CFTR function.
She runs a clinic which accepts referrals from throughout France for questionable diagnosis for CF.
She is involved in the European Clinical Trial Network as head of the standardization committee.
She also works closely with Aleksander Edelman laboratory where she completed her phD.
She has been engaged in new CFTR corrector design, studies in the murine animal model and is now co-heading with Aleksander Edelman the group.